Alanosine

Chemical compound

None

Identifiers

IUPAC name

(S)-2-Amino-3-[hydroxy(nitroso)amino]propanoic acid

CAS Number

5854-93-3^Y

PubChem CID

22128

ChemSpider

20787^Y

UNII

2CNI71214Y

ChEMBL

ChEMBL452715^Y

CompTox Dashboard (EPA)

DTXSID501024175

Chemical and physical dataFormulaC₃H₇N₃O₄Molar mass149.106 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

O=C(O)[C@@H](N)CN(O)N=O

InChI

InChI=1S/C3H7N3O4/c4-2(3(7)8)1-6(10)5-9/h2,10H,1,4H2,(H,7,8)/t2-/m0/s1^Y
Key:MLFKVJCWGUZWNV-REOHCLBHSA-N^Y

(verify)

Alanosine (also called SDX-102)^[1] is a substance that has been studied for the treatment of pancreatic cancer.^[2] It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.^{[needs update]}

References

^ PubChem. "Alanosine". pubchem.ncbi.nlm.nih.gov. Retrieved 2021-04-08.
^ Yu J (November 2001). "Alanosine (UCSD)". Current Opinion in Investigational Drugs. 2 (11): 1623–30. PMID 11763167.