MICU1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4NSC, 4NSD |
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Identifiers |
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Aliases | MICU1, CALC, CBARA1, EFHA3, MPXPS, mitochondrial calcium uptake 1, ara CALC |
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External IDs | OMIM: 605084; MGI: 2384909; HomoloGene: 4431; GeneCards: MICU1; OMA:MICU1 - orthologs |
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Gene location (Human) |
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![Chromosome 10 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/300px-Ideogram_human_chromosome_10.svg.png) | Chr. | Chromosome 10 (human)[1] |
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| Band | 10q22.1 | Start | 72,367,340 bp[1] |
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End | 72,626,131 bp[1] |
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Gene location (Mouse) |
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![Chromosome 10 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_house_mouse_chromosome_10.svg/260px-Ideogram_house_mouse_chromosome_10.svg.png) | Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10|10 B4 | Start | 59,538,299 bp[2] |
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End | 59,699,954 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Achilles tendon
- cerebellar hemisphere
- right hemisphere of cerebellum
- right adrenal cortex
- monocyte
- left adrenal gland
- right frontal lobe
- gastrocnemius muscle
- left adrenal cortex
- prefrontal cortex
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| Top expressed in | - intestinal villus
- neural layer of retina
- dentate gyrus of hippocampal formation granule cell
- granulocyte
- pyloric antrum
- lens
- mucous cell of stomach
- zygote
- duodenum
- muscle of thigh
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/PBB_GE_CBARA1_216903_s_at_fs.png/250px-PBB_GE_CBARA1_216903_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - calcium ion binding
- metal ion binding
- protein binding
- identical protein binding
- protein heterodimerization activity
| Cellular component | - calcium channel complex
- membrane
- mitochondrial intermembrane space
- intracellular anatomical structure
- mitochondrion
- uniplex complex
- integral component of mitochondrial membrane
- integral component of membrane
- mitochondrial inner membrane
| Biological process | - defense response
- calcium ion import
- mitochondrial calcium ion homeostasis
- ion transport
- calcium import into the mitochondrion
- positive regulation of mitochondrial calcium ion concentration
- protein homooligomerization
- calcium ion transport
- mitochondrial calcium ion transmembrane transport
- regulation of cellular hyperosmotic salinity response
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001195518 NM_001195519 NM_006077 NM_001363513 |
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NM_001291442 NM_001291443 NM_144822 NM_001359267 |
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RefSeq (protein) | |
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NP_001182447 NP_001182448 NP_006068 NP_001350442 |
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NP_001278371 NP_001278372 NP_659071 NP_001346196 |
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Location (UCSC) | Chr 10: 72.37 – 72.63 Mb | Chr 10: 59.54 – 59.7 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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