GUCY1A1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3UVJ, 4NI2 |
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Identifiers |
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Aliases | GUCY1A1, MYMY6, GC-SA3, GUCY1A3, GUCSA3, guanylate cyclase 1 soluble subunit alpha, guanylate cyclase 1 soluble subunit alpha 1, guanylate cyclase 1, soluble, alpha 3, GUC1A3, GUCA3 |
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External IDs | OMIM: 139396; MGI: 1926562; HomoloGene: 37360; GeneCards: GUCY1A1; OMA:GUCY1A1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 4 (human)[1] |
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| Band | 4q32.1 | Start | 155,666,711 bp[1] |
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End | 155,732,349 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 E3 | Start | 81,999,734 bp[2] |
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End | 82,053,096 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - urethra
- vena cava
- saphenous vein
- visceral pleura
- myocardium
- right ventricle
- superficial temporal artery
- lower lobe of lung
- lactiferous duct
- middle temporal gyrus
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| Top expressed in | - olfactory tubercle
- left lung lobe
- habenula
- Gonadal ridge
- ascending aorta
- aortic valve
- nucleus accumbens
- atrium
- atrioventricular valve
- right lung lobe
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - nucleotide binding
- guanylate cyclase activity
- GTP binding
- protein binding
- heme binding
- lyase activity
- phosphorus-oxygen lyase activity
- signaling receptor activity
- adenylate cyclase activity
| Cellular component | - cytoplasm
- plasma membrane
- guanylate cyclase complex, soluble
- glutamatergic synapse
- GABA-ergic synapse
| Biological process | - intracellular signal transduction
- cyclic nucleotide biosynthetic process
- blood circulation
- regulation of blood pressure
- cGMP biosynthetic process
- relaxation of vascular associated smooth muscle
- nitric oxide mediated signal transduction
- positive regulation of nitric oxide mediated signal transduction
- retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_000856 NM_001130682 NM_001130683 NM_001130684 NM_001130685
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NM_001130686 NM_001130687 NM_001256449 |
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NM_021896 NM_001356987 NM_001356988 |
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RefSeq (protein) | NP_000847 NP_001124154 NP_001124155 NP_001124156 NP_001124157
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NP_001124159 NP_001243378 NP_001366595 NP_001366596 NP_001366597 NP_001366598 NP_001366599 NP_001366600 NP_001366601 NP_001366602 NP_001366603 NP_001366604 NP_001366605 |
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NP_068696 NP_001343916 NP_001343917 |
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Location (UCSC) | Chr 4: 155.67 – 155.73 Mb | Chr 3: 82 – 82.05 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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