MARCHF7 |
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Identifiers |
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Aliases | MARCHF7, AXO, AXOT, MARCH-VII, RNF177, membrane associated ring-CH-type finger 7, MARCH7 |
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External IDs | OMIM: 613334; MGI: 1931053; HomoloGene: 10753; GeneCards: MARCHF7; OMA:MARCHF7 - orthologs |
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Gene location (Human) |
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![Chromosome 2 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Ideogram_human_chromosome_2.svg/300px-Ideogram_human_chromosome_2.svg.png) | Chr. | Chromosome 2 (human)[1] |
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| Band | 2q24.2 | Start | 159,712,457 bp[1] |
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End | 159,771,027 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - Achilles tendon
- amniotic fluid
- ventricular zone
- gingival epithelium
- secondary oocyte
- oral cavity
- germinal epithelium
- ganglionic eminence
- gallbladder
- epithelium of nasopharynx
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| | More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/f/fe/PBB_GE_MARCH7_202654_x_at_fs.png/250px-PBB_GE_MARCH7_202654_x_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/3/33/PBB_GE_MARCH7_202653_s_at_fs.png/250px-PBB_GE_MARCH7_202653_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - zinc ion binding
- metal ion binding
- transferase activity
- enzyme binding
- ubiquitin conjugating enzyme binding
- ubiquitin binding
- MDM2/MDM4 family protein binding
- protein binding
| Cellular component | - nucleus
- cytosol
- plasma membrane
| Biological process | - negative regulation of T cell proliferation
- regulation of tolerance induction
- protein ubiquitination
- positive regulation of cell population proliferation
- negative regulation of DNA damage response, signal transduction by p53 class mediator
- protein stabilization
- protein autoubiquitination
- negative regulation of proteasomal protein catabolic process
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
- positive regulation of protein polyubiquitination
- negative regulation of protein autoubiquitination
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001282805 NM_001282806 NM_001282807 NM_022826 |
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RefSeq (protein) | NP_001269734 NP_001269735 NP_001269736 NP_073737 NP_001363163
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NP_001363164 NP_001363165 NP_001363166 NP_001363167 NP_001363168 NP_001363169 NP_001363170 NP_001363171 NP_001363172 NP_001363173 NP_001363174 NP_001363175 NP_001363176 NP_001363177 NP_001363178 NP_001363179 NP_001363180 NP_001363181 NP_001363182 NP_001363183 NP_001363184 |
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Location (UCSC) | Chr 2: 159.71 – 159.77 Mb | n/a |
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PubMed search | [2] | [3] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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