NEK1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4APC, 4B9D |
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Identifiers |
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Aliases | NEK1, NY-REN-55, SRPS2, SRPS2A, SRTD6, NIMA related kinase 1, ALS24 |
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External IDs | OMIM: 604588; MGI: 97303; HomoloGene: 14376; GeneCards: NEK1; OMA:NEK1 - orthologs |
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Gene location (Human) |
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![Chromosome 4 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Ideogram_human_chromosome_4.svg/300px-Ideogram_human_chromosome_4.svg.png) | Chr. | Chromosome 4 (human)[1] |
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| Band | 4q33 | Start | 169,369,704 bp[1] |
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End | 169,612,632 bp[1] |
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Gene location (Mouse) |
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![Chromosome 8 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Ideogram_house_mouse_chromosome_8.svg/260px-Ideogram_house_mouse_chromosome_8.svg.png) | Chr. | Chromosome 8 (mouse)[2] |
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| Band | 8 B3.1|8 30.91 cM | Start | 61,446,229 bp[2] |
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End | 61,584,380 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - secondary oocyte
- trigeminal ganglion
- spinal ganglia
- optic nerve
- sural nerve
- internal globus pallidus
- sperm
- pars reticulata
- Pars compacta
- lactiferous duct
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| Top expressed in | - sciatic nerve
- zygote
- secondary oocyte
- vestibular sensory epithelium
- trigeminal ganglion
- facial motor nucleus
- cumulus cell
- lumbar spinal ganglion
- iris
- ciliary body
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/2/29/PBB_GE_NEK1_213328_at_fs.png/250px-PBB_GE_NEK1_213328_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/c/c3/PBB_GE_NEK1_211086_x_at_fs.png/250px-PBB_GE_NEK1_211086_x_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/6/66/PBB_GE_NEK1_213331_s_at_fs.png/250px-PBB_GE_NEK1_213331_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- protein kinase activity
- nucleotide binding
- metal ion binding
- kinase activity
- protein binding
- protein tyrosine kinase activity
- ATP binding
- protein serine/threonine kinase activity
- 14-3-3 protein binding
| Cellular component | - cytoplasm
- centrosome
- pericentriolar material
- microtubule organizing center
- cytoskeleton
- nucleus
| Biological process | - phosphorylation
- cell division
- protein phosphorylation
- cell projection organization
- cell cycle
- peptidyl-tyrosine phosphorylation
- cilium assembly
- regulation of mitotic cell cycle
- signal transduction
- stress-activated protein kinase signaling cascade
- activation of protein kinase activity
- regulation of apoptotic process
- cellular response to DNA damage stimulus
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001199397 NM_001199398 NM_001199399 NM_001199400 NM_012224
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NM_001374418 NM_001374419 NM_001374420 NM_001374421 NM_001374422 NM_001374423 |
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NM_001293637 NM_001293638 NM_001293639 NM_175089 |
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RefSeq (protein) | NP_001186326 NP_001186327 NP_001186328 NP_001186329 NP_036356
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NP_001361347 NP_001361348 NP_001361349 NP_001361350 NP_001361351 NP_001361352 |
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NP_001280566 NP_001280567 NP_001280568 NP_780298 |
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Location (UCSC) | Chr 4: 169.37 – 169.61 Mb | Chr 8: 61.45 – 61.58 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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