NUPR1 |
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Identifiers |
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Aliases | NUPR1, COM1, P8, nuclear protein 1, transcriptional regulator |
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External IDs | OMIM: 614812; MGI: 1891834; HomoloGene: 8229; GeneCards: NUPR1; OMA:NUPR1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 16 (human)[1] |
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| Band | 16p11.2 | Start | 28,532,708 bp[1] |
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End | 28,539,008 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 F3 | Start | 126,222,421 bp[2] |
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End | 126,230,033 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - left lobe of thyroid gland
- right lobe of thyroid gland
- body of pancreas
- right adrenal cortex
- gastric mucosa
- left adrenal cortex
- muscle layer of sigmoid colon
- skin of abdomen
- skin of leg
- right lung
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| Top expressed in | - submandibular gland
- epithelium of lens
- lacrimal gland
- calvaria
- crypt of lieberkuhn of small intestine
- tunica media of zone of aorta
- ascending aorta
- epithelium of stomach
- parotid gland
- pyloric antrum
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - chromatin binding
- DNA binding
- protein binding
- transcription coactivator activity
- acetyltransferase activator activity
| Cellular component | - nucleus
- cytosol
- protein-DNA complex
- cytoplasm
- perinuclear region of cytoplasm
| Biological process | - skeletal muscle cell differentiation
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
- negative regulation of cell cycle
- male gonad development
- regulation of transcription, DNA-templated
- acute inflammatory response
- negative regulation of fibroblast proliferation
- regulation of female gonad development
- response to toxic substance
- transcription, DNA-templated
- protein acetylation
- positive regulation of protein modification process
- positive regulation of apoptotic process
- regulation of transcription by RNA polymerase II
- cell population proliferation
- protein-containing complex assembly
- negative regulation of cell population proliferation
- positive regulation of catalytic activity
- positive regulation of proteasomal protein catabolic process
- positive regulation of nucleic acid-templated transcription
- regulation of autophagy
- negative regulation of autophagy
- negative regulation of cardiac muscle cell apoptotic process
- negative regulation of apoptotic process
- negative regulation of DNA-binding transcription factor activity
- positive regulation of neuron apoptotic process
- negative regulation of glycolytic process
- negative regulation of epithelial cell proliferation
- negative regulation of programmed necrotic cell death
- positive regulation of neuroinflammatory response
- negative regulation of autophagosome assembly
- positive regulation of oxidative phosphorylation
- negative regulation of epithelial cell apoptotic process
- negative regulation of type B pancreatic cell proliferation
- regulation of response to endoplasmic reticulum stress
- positive regulation of intrinsic apoptotic signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 16: 28.53 – 28.54 Mb | Chr 7: 126.22 – 126.23 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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