Synthase
Enzyme that catalyses a synthesis process
In biochemistry, a synthase is an enzyme that catalyses a synthesis process.
Note that, originally, biochemical nomenclature distinguished synthetases and synthases. Under the original definition, synthases do not use energy from nucleoside triphosphates (such as ATP, GTP, CTP, TTP, and UTP), whereas synthetases do use nucleoside triphosphates. However, the Joint Commission on Biochemical Nomenclature (JCBN) dictates that 'synthase' can be used with any enzyme that catalyzes synthesis (whether or not it uses nucleoside triphosphates), whereas 'synthetase' is to be used synonymously with 'ligase'.[1]
Examples
- ATP synthase
- Citrate synthase
- Tryptophan synthase
- Pseudouridine synthase
- Fatty acid synthase
- Cellulose synthase (UDP-forming)
- Cellulose synthase (GDP-forming)
References
- ^ "Synthase and ligase". Archived from the original on 2012-10-15. Retrieved 2009-06-02.
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Enzymes
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Diffusion-limited enzyme
- Cofactor
- Enzyme catalysis
- EC1 Oxidoreductases (list)
- EC2 Transferases (list)
- EC3 Hydrolases (list)
- EC4 Lyases (list)
- EC5 Isomerases (list)
- EC6 Ligases (list)
- EC7 Translocases (list)
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