Trimedoxime bromide
Chemical compound
- None
- Experimental; in military use
- 1,1′-propane-1,3-diylbis{4-[(E)-(hydroxyimino)methyl]pyridinium} dibromide
- 56-97-3
- 5359236
- 4514238
- ED0GXI9825
- DTXSID101036063
Trimedoxime bromide (INN), also known as dipyroxime or TMB-4, is an oxime used in the treatment of organophosphate poisoning[1] It is chemically related to asoxime, pralidoxime, and obidoxime.[2]
References
- ^ Dhuguru J, Zviagin E, Skouta R (January 2022). "FDA-Approved Oximes and Their Significance in Medicinal Chemistry". Pharmaceuticals. 15 (1). Basel, Switzerland: 66. doi:10.3390/ph15010066. PMC 8779982. PMID 35056123.
- ^ Gupta R, Parmar M (2022). "Pralidoxime". StatPearls. Treasure Island (FL): StatPearls Publishing. PMID 32644334.
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Antidotes (V03AB)
system
Alcohol intoxication |
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Barbiturate overdose | |
Benzodiazepine overdose | |
GHB overdose | |
Nerve agent / Organophosphate poisoning |
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Opioid overdose | |
Reversal of neuromuscular blockade |
system
Beta blocker | |
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Digoxin toxicity | |
Anticoagulants |
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Arsenic poisoning | |
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Cyanide poisoning |
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Hydrofluoric acid | |
Methanol / Ethylene glycol poisoning |
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Paracetamol toxicity (Acetaminophen) | |
Toxic metals (cadmium | |
Other |
- Copper sulfate
- Ipecacuanha
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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