USP22 |
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Identifiers |
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Aliases | USP22, USP3L, ubiquitin specific peptidase 22 |
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External IDs | OMIM: 612116; MGI: 2144157; HomoloGene: 52664; GeneCards: USP22; OMA:USP22 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17p11.2 | Start | 20,999,596 bp[1] |
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End | 21,043,760 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B2 | Start | 61,042,611 bp[2] |
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End | 61,065,881 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - paraflocculus of cerebellum
- ganglionic eminence
- middle frontal gyrus
- frontal pole
- stromal cell of endometrium
- Brodmann area 10
- ventricular zone
- right hemisphere of cerebellum
- cingulate gyrus
- anterior cingulate cortex
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| Top expressed in | - ganglionic eminence
- medial ganglionic eminence
- paraventricular nucleus of hypothalamus
- arcuate nucleus
- dentate gyrus of hippocampal formation granule cell
- dorsomedial hypothalamic nucleus
- ventromedial nucleus
- medial geniculate nucleus
- anterior amygdaloid area
- subiculum
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - cysteine-type peptidase activity
- transcription coactivator activity
- zinc ion binding
- H4 histone acetyltransferase activity
- metal ion binding
- peptidase activity
- protein binding
- nuclear receptor coactivator activity
- thiol-dependent deubiquitinase
- enzyme binding
- hydrolase activity
| Cellular component | - SAGA-type complex
- SAGA complex
- nucleus
- nucleoplasm
- nuclear speck
| Biological process | - regulation of transcription, DNA-templated
- ubiquitin-dependent protein catabolic process
- positive regulation of mitotic cell cycle
- transcription, DNA-templated
- proteolysis
- positive regulation of transcription, DNA-templated
- histone deubiquitination
- cell cycle
- histone ubiquitination
- histone H4 acetylation
- protein deubiquitination
- embryo development ending in birth or egg hatching
- chromatin organization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 17: 21 – 21.04 Mb | Chr 11: 61.04 – 61.07 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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