PKP2 |
---|
|
Structures disponibles |
---|
PDB | Recherche d'orthologue: PDBe RCSB |
---|
Identifiants PDB |
---|
3TT9,%%s3TT9 |
|
|
Identifiants |
---|
Aliases | PKP2 |
---|
IDs externes | OMIM: 602861 MGI: 1914701 HomoloGene: 3364 GeneCards: PKP2 |
---|
Position du gène (Homme) |
---|
| Chr. | Chromosome 12 humain[1] |
---|
| Locus | 12p11.21 | Début | 32,790,755 bp[1] |
---|
Fin | 32,896,777 bp[1] |
---|
|
Position du gène (Souris) |
---|
| Chr. | Chromosome 16 (souris)[2] |
---|
| Locus | 16|16 A2 | Début | 16,031,182 bp[2] |
---|
Fin | 16,090,576 bp[2] |
---|
|
Expression génétique |
---|
Bgee | Humain | Souris (orthologue) |
---|
Fortement exprimé dans | - ventricule droit
- apex of heart
- myocardium of left ventricle
- right uterine tube
- auricule droit
- cardiac muscle tissue of right atrium
- mucosa of colon
- mucosa of sigmoid colon
- rectum
- mucosa of transverse colon
|
| Fortement exprimé dans | - Ileal epithelium
- superior surface of tongue
- vésicule biliaire
- valve auriculo-ventriculaire
- myocardium of ventricle
- cardiac muscle tissue of left ventricle
- endocardial cushion
- atrium
- Cellule de Paneth
- epithelium of lens
|
| Plus de données d'expression de référence |
|
---|
BioGPS |
| Plus de données d'expression de référence |
|
---|
|
Gene Ontology |
---|
Fonction moléculaire | - sodium channel regulator activity
- intermediate filament binding
- transmembrane transporter binding
- liaison protéique
- cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication
- molecular adaptor activity
- alpha-catenin binding
- protein kinase C binding
- cadherin binding
| Composant cellulaire | - integral component of membrane
- intercalated disc
- jonction cellule-cellule
- zonula adherens
- membrane plasmique
- desmosome
- nucléoplasme
- jonction cellulaire
- Filament intermédiaire
- noyau
- cornified envelope
- messenger ribonucleoprotein complex
- cytoplasme
| Processus biologique | - intermediate filament bundle assembly
- cell communication by electrical coupling involved in cardiac conduction
- ventricular cardiac muscle cell action potential
- cardiac muscle cell action potential involved in contraction
- bundle of His cell-Purkinje myocyte adhesion involved in cell communication
- cell-cell signaling involved in cardiac conduction
- ventricular cardiac muscle tissue morphogenesis
- développement du cœur
- desmosome assembly
- adhésion cellulaire
- positive regulation of sodium ion transport
- regulation of heart rate by cardiac conduction
- regulation of ventricular cardiac muscle cell action potential
- maintenance of animal organ identity
- keratinization
- cornification
- protein localization to plasma membrane
- cell-cell adhesion
- cell-cell junction assembly
- adherens junction maintenance
| Sources:Amigo / QuickGO |
|
Orthologues |
---|
Espèces | Homme | Souris |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | | |
---|
RefSeq (protéine) | | |
---|
Localisation (UCSC) | Chr 12: 32.79 – 32.9 Mb | Chr 16: 16.03 – 16.09 Mb |
---|
Publication PubMed | [3] | [4] |
---|
|
Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
|