CTNNAL1

Pengidentifikasi

Alias

CTNNAL1, ACRP, CLLP, alpha-CATU, catenin alpha like 1

ID eksternal

OMIM: 604785 MGI: 1859649 HomoloGene: 2815 GeneCards: CTNNAL1

Pola ekspresi RNA

Referensi data ekspresi selengkapnya

Ontologi gen
Fungsi molekuler	• actin filament binding • GO:0001948, GO:0016582 Ikatan protein plasma • cadherin binding
Komponen seluler	• sitoplasma • sitosol • Membran sel • Sitoskeleton • membran
Proses biologis	• Adhesi sel • Rho protein signal transduction
Sumber:Amigo / QuickGO

Ortolog

Spesies

Manusia

Tikus

Entrez


8727


54366

Ensembl


ENSG00000119326


ENSMUSG00000038816

UniProt


Q9UBT7


O88327

RefSeq (mRNA)


NM_001286974 NM_003798


NM_018761

RefSeq (protein)


NP_001273903 NP_003789


NP_061231

Lokasi (UCSC)

n/a

Pencarian PubMed

^[1]

^[2]

Wikidata

Lihat/Sunting Manusia

Lihat/Sunting Tikus

Alpha-catulin adalah protein yang pada manusia dikodekan oleh gen CTNNAL1.^[3]^[4]

Interaksi

CTNNAL1 telah terbukti berinteraksi dengan AKAP13.^[5]

Referensi

^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI (Jan 1999). "Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin". Genomics. 54 (1): 149–54. doi:10.1006/geno.1998.5458. PMID 9806841.
^ "Entrez Gene: CTNNAL1 catenin (cadherin-associated protein), alpha-like 1".
^ Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (Nov 2002). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200 . PMID 12270917.

Pranala luar

Lokasi genom CTNNAL1 manusia dan halaman rincian gen CTNNAL1 dalam UCSC Genome Browser.

Bacaan lanjutan

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Janssens B, Staes K, van Roy F (1999). "Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing". Biochim. Biophys. Acta. 1447 (2–3): 341–7. doi:10.1016/s0167-4781(99)00170-0. PMID 10542337.
Demacio PC, Ray PN (2002). "Alpha-catulin maps to the familial dysautonomia region on 9q31". Genome. 44 (6): 990–4. doi:10.1139/gen-44-6-990. PMID 11768226.
Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (2003). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200 . PMID 12270917.
Shieh YS, Chang LC, Chiu KC, Wu CW, Lee HS (2003). "Cadherin and catenin expression in mucoepidermoid carcinoma: correlation with histopathologic grade, clinical stage, and patient outcome". J. Oral Pathol. Med. 32 (5): 297–304. doi:10.1034/j.1600-0714.2003.00144.x. PMID 12694354.
Surpili MJ, Delben TM, Kobarg J (2004). "Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1". Biochemistry. 42 (51): 15369–76. doi:10.1021/bi034575v. PMID 14690447.
Merdek KD, Nguyen NT, Toksoz D (2004). "Distinct Activities of the α-Catenin Family, α-Catulin and α-Catenin, on β-Catenin-Mediated Signaling". Mol. Cell. Biol. 24 (6): 2410–22. doi:10.1128/mcb.24.6.2410-2422.2004. PMC 355851 . PMID 14993280.