Gingipain K

Identifikatori

EC broj

3.4.22.47

159745-69-4

Baze podataka

IntEnz

IntEnz pregled

BRENDA

BRENDA pristup

ExPASy

NiceZyme pregled

KEGG

KEGG pristup

MetaCyc

metabolički put

profil

Strukture PBP

RCSB PDB PDBe PDBj PDBsum

Gingipain K (EC 3.4.22.47, Lys-gingipain, PrtP proteinaza) je enzim.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Endopeptidaza sa striktnom specifičnošću za for lizinske veze

Aktivnost ovog enzima stimuliše glicin.

Reference

^ Pike, R., McGraw, W., Potempa, J. and Travis, J. (1994). „Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins”. J. Biol. Chem. 269: 406—411. PMID 8276827. CS1 одржавање: Вишеструка имена: списак аутора (веза)
^ Curtis, M.A., Aduse, O.J., Rangarajan, M., Gallagher, A., Sterne, J.A., Reid, C.R., Evans, H.E. and Samuelsson, B. (2002). „Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor 2”. Infect. Immun. 70: 6968—6975. PMID 12438376. CS1 одржавање: Вишеструка имена: списак аутора (веза)

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Gingipain+K на US National Library of Medicine Medical Subject Headings (MeSH)

Teme

Tipovi

B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6