Nikofuranoza : Osobine, Reference, Literatura, Spoljašnje veze Википедија

Nikofuranoza

Nikofuranoza
Klinički podaci

Drugs.com	Monografija
Identifikatori
ATC kod	C10AD03 (WHO)
PubChem	CID 25495
UNII	GF99P6327K^Y
KEGG	D07189^Y
Hemijski podaci
Formula	C₃₀H₂₄N₄O₁₀
Molarna masa	600,532
SMILES O[C@]1(COC(=O)c2cccnc2)O[C@H](COC(=O)c3cccnc3)[C@@H](OC(=O)c4cccnc4)[C@@H]1OC(=O)c5cccnc5
InChI InChI=1S/C30H24N4O10/c35-26(19-5-1-9-31-13-19)40-17-23-24(42-28(37)21-7-3-11-33-15-21)25(43-29(38)22-8-4-12-34-16-22)30(39,44-23)18-41-27(36)20-6-2-10-32-14-20/h1-16,23-25,39H,17-18H2/t23-,24-,25+,30-/m1/s1^Y Key:FUWFSXZKBMCSKF-ZASNTINBSA-N^Y

Nikofuranoza je organsko jedinjenje, koje sadrži 30 atoma ugljenika i ima molekulsku masu od 600,532 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	14
Broj donora vodonika	1
Broj rotacionih veza	14
Particioni koeficijent^[1] (ALogP)	1,0
Rastvorljivost^[2] (logS, log(mol/L))	-5,7
Polarna površina^[3] (PSA, Å²)	186,2

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.