HEY2 |
---|
|
معرفات |
---|
أسماء بديلة | HEY2, CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, bHLHb32, hes related family bHLH transcription factor with YRPW motif 2 |
---|
معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 604674 MGI: MGI:1341884 HomoloGene: 22705 GeneCards: 23493 |
---|
علم الوجود الجيني |
---|
وظائف جزيئية | • microsatellite binding • sequence-specific DNA binding • ربط دي إن إي • protein dimerization activity • protein homodimerization activity • GO:0001131، GO:0001151، GO:0001130، GO:0001204 DNA-binding transcription factor activity • transcription factor binding • histone deacetylase binding • GO:0000983 RNA polymerase II general transcription initiation factor activity • GO:0001948، GO:0016582 ربط بروتيني • protein heterodimerization activity • GO:0001200، GO:0001133، GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001077، GO:0001212، GO:0001213، GO:0001211، GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001078، GO:0001214، GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001106 transcription corepressor activity • sequence-specific double-stranded DNA binding |
---|
مكونات خلوية | • سيتوبلازم • transcription repressor complex • Sin3 complex • بلازم نووي • نواة |
---|
عمليات حيوية | • dorsal aorta morphogenesis • cardiac vascular smooth muscle cell development • cochlea development • pattern specification process • cell fate commitment • pulmonary valve morphogenesis • regulation of inner ear auditory receptor cell differentiation • negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation • GO:0009373 ضبط نسخ الدنا • heart trabecula formation • tricuspid valve morphogenesis • regulation of vasculogenesis • pulmonary artery morphogenesis • cardiac septum morphogenesis • negative regulation of cardiac vascular smooth muscle cell differentiation • muscular septum morphogenesis • ventricular septum morphogenesis • protein-DNA complex assembly • cardiac muscle hypertrophy • outflow tract morphogenesis • ascending aorta morphogenesis • cardiac left ventricle morphogenesis • labyrinthine layer blood vessel development • GO:1901227 negative regulation of transcription by RNA polymerase II • coronary vasculature morphogenesis • smooth muscle cell differentiation • negative regulation of gene expression • endocardial cushion to mesenchymal transition involved in heart valve formation • نسخ الدنا • ventricular trabecula myocardium morphogenesis • positive regulation of heart rate • تكون الأوعية • نمو متعدد الخلايا • atrial septum morphogenesis • negative regulation of cardiac muscle cell apoptotic process • نماء القلب • arterial endothelial cell differentiation • positive regulation of cardiac muscle cell proliferation • blood vessel development • cardiac muscle hypertrophy in response to stress • umbilical cord morphogenesis • negative regulation of transcription regulatory region DNA binding • mesenchymal cell development • artery development • تنظيم التعبير الجيني • negative regulation of transcription by transcription factor localization • negative regulation of transcription initiation from RNA polymerase II promoter • vascular associated smooth muscle cell development • anterior/posterior axis specification • tricuspid valve formation • GO:0045996 negative regulation of transcription, DNA-templated • cardiac ventricle morphogenesis • cardiac right ventricle morphogenesis • ventricular cardiac muscle cell development • atrioventricular valve development • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني • negative regulation of Notch signaling pathway • cardiac epithelial to mesenchymal transition • Notch signaling involved in heart development • Notch signaling pathway • GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated • تمايز خلوي • regulation of neurogenesis • aortic valve morphogenesis • epithelial to mesenchymal transition involved in endocardial cushion formation • GO:1901313 positive regulation of gene expression • negative regulation of biomineral tissue development • نقل شاردة الكالسيوم • circulatory system development |
---|
المصادر:Amigo / QuickGO | |
نمط التعبير عن الحمض النووي الريبوزي |
---|
|
المزيد من بيانات التعبير المرجعية |
تماثلات متسلسلة |
---|
أنواع | الإنسان | الفأر |
---|
أنتريه | 23493 | 15214 |
---|
Ensembl | ENSG00000135547 | ENSMUSG00000019789 |
---|
يونيبروت | | |
---|
RefSeq (رنا مرسال.) | | XM_017010627، XM_017010628 NM_012259، XM_017010627، XM_017010628 |
| |
---|
RefSeq (بروتين) | | XP_016866116، XP_016866117، XP_016866118 NP_036391، XP_016866116، XP_016866117، XP_016866118 XP_011533952.1 |
| |
---|
الموقع (UCSC | n/a | Chr 10: 30.71 – 30.72 Mb |
---|
بحث ببمد | [1] | [2] |
---|
ويكي بيانات |
اعرض/عدّل إنسان | اعرض/عدّل فأر |
|