ARD1A
N(alfa)-acetiltransferaza 10, NatA katalitička podjedinica | |||||||||||
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Identifikatori | |||||||||||
Simboli | NAA10; ARD1; ARD1A; DXS707; NATD; TE2 | ||||||||||
Vanjski ID | OMIM: 300013 MGI: 1915255 HomoloGene: 2608 GeneCards: NAA10 Gene | ||||||||||
EC broj | 2.3.1.88 | ||||||||||
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Pregled RNK izražavanja | |||||||||||
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podaci | |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 8260 | 56292 | |||||||||
Ensembl | ENSG00000102030 | ENSMUSG00000031388 | |||||||||
UniProt | P41227 | Q9QY36 | |||||||||
RefSeq (mRNA) | NM_001256119 | NM_001177965 | |||||||||
RefSeq (protein) | NP_001243048 | NP_001171436 | |||||||||
Lokacija (UCSC) | Chr HG1497_PATCH: 153.14 - 153.14 Mb | Chr X: 73.92 - 73.92 Mb | |||||||||
PubMed pretraga | [1] | [2] |
N-terminalni acetiltransferazni kompleks ARD1, homolog A je enzim koji je kod čoveka kodiran ARD1A genom.[1][2]
Reference
- ^ Tribioli C, Mancini M, Plassart E, Bione S, Rivella S, Sala C, Torri G, Toniolo D (1995). „Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae”. Hum Mol Genet. 3 (7): 1061—7. PMID 7981673. doi:10.1093/hmg/3.7.1061.
- ^ „Entrez Gene: ARD1A ARD1 homolog A, N-acetyltransferase (S. cerevisiae)”.
Literatura
- Brenner V, Nyakatura G, Rosenthal A, Platzer M (1997). „Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse.”. Genomics. 44 (1): 8—14. PMID 9286695. doi:10.1006/geno.1997.4822.
- Hartley JL, Temple GF, Brasch MA (2001). „DNA cloning using in vitro site-specific recombination.”. Genome Res. 10 (11): 1788—95. PMC 310948
. PMID 11076863. doi:10.1101/gr.143000.
- Simpson JC; Wellenreuther R; Poustka A; et al. (2001). „Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.”. EMBO Rep. 1 (3): 287—92. PMC 1083732
. PMID 11256614. doi:10.1093/embo-reports/kvd058.
- Jeong JW; Bae MK; Ahn MY; et al. (2003). „Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation.”. Cell. 111 (5): 709—20. PMID 12464182. doi:10.1016/S0092-8674(02)01085-1.
- Strausberg RL; Feingold EA; Grouse LH; et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899—903. PMC 139241
. PMID 12477932. doi:10.1073/pnas.242603899.
- Sugiura N, Adams SM, Corriveau RA (2003). „An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development.”. J. Biol. Chem. 278 (41): 40113—20. PMID 12888564. doi:10.1074/jbc.M301218200.
- Gerhard DS; Wagner L; Feingold EA; et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121—7. PMC 528928
. PMID 15489334. doi:10.1101/gr.2596504.
- Wiemann S; Arlt D; Huber W; et al. (2004). „From ORFeome to biology: a functional genomics pipeline.”. Genome Res. 14 (10B): 2136—44. PMC 528930
. PMID 15489336. doi:10.1101/gr.2576704.
- Arnesen T; Anderson D; Baldersheim C; et al. (2005). „Identification and characterization of the human ARD1-NATH protein acetyltransferase complex.”. Biochem. J. 386 (Pt 3): 433—43. PMC 1134861
. PMID 15496142. doi:10.1042/BJ20041071.
- Asaumi M; Iijima K; Sumioka A; et al. (2005). „Interaction of N-terminal acetyltransferase with the cytoplasmic domain of beta-amyloid precursor protein and its effect on A beta secretion.”. J. Biochem. 137 (2): 147—55. PMID 15749829. doi:10.1093/jb/mvi014.
- Fisher TS; Etages SD; Hayes L; et al. (2005). „Analysis of ARD1 function in hypoxia response using retroviral RNA interference.”. J. Biol. Chem. 280 (18): 17749—57. PMID 15755738. doi:10.1074/jbc.M412055200.
- Bilton R; Mazure N; Trottier E; et al. (2005). „Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF.”. J. Biol. Chem. 280 (35): 31132—40. PMID 15994306. doi:10.1074/jbc.M504482200.
- Rual JF; Venkatesan K; Hao T; et al. (2005). „Towards a proteome-scale map of the human protein-protein interaction network.”. Nature. 437 (7062): 1173—8. PMID 16189514. doi:10.1038/nature04209.
- Arnesen T; Gromyko D; Horvli O; et al. (2006). „Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.”. Thyroid. 15 (10): 1131—6. PMID 16279846. doi:10.1089/thy.2005.15.1131.
- Arnesen T; Kong X; Evjenth R; et al. (2006). „Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha.”. FEBS Lett. 579 (28): 6428—32. PMID 16288748. doi:10.1016/j.febslet.2005.10.036.
- Kim SH; Park JA; Kim JH; et al. (2006). „Characterization of ARD1 variants in mammalian cells.”. Biochem. Biophys. Res. Commun. 340 (2): 422—7. PMID 16376303. doi:10.1016/j.bbrc.2005.12.018.
- Mehrle A; Rosenfelder H; Schupp I; et al. (2006). „The LIFEdb database in 2006.”. Nucleic Acids Res. 34 (Database issue): D415—8. PMC 1347501
. PMID 16381901. doi:10.1093/nar/gkj139.
- Arnesen T; Gromyko D; Pendino F; et al. (2006). „Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex.”. Oncogene. 25 (31): 4350—60. PMID 16518407. doi:10.1038/sj.onc.1209469.
- Beausoleil SA; Villén J; Gerber SA; et al. (2006). „A probability-based approach for high-throughput protein phosphorylation analysis and site localization.”. Nat. Biotechnol. 24 (10): 1285—92. PMID 16964243. doi:10.1038/nbt1240.
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
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acetiltransferaze: Acetil-koenzime A acetiltransferaza - N-Acetilglutamat sintaza - Holin acetiltransferaza - Dihidrolipoil transacetilaza - Acetil-CoA C-aciltransferaza - Beta-galaktozid transacetilaza - hloramfenikol acetiltransferaza - N-acetiltransferaza (Serotonin N-acetil transferaza, HGSNAT, ARD1A) - Histon acetiltransferaza (P300/CBP, NAT2)
palmitoiltransferaze: Karnitin O-palmitoiltransferaza (CPT1, CPT2) - Serin C-palmitoiltransferaza (SPTLC1, SPTLC2)
druge: Aciltransferazi slična 2 - Sintaza aminolevulinske kiseline - Beta-ketoacil-ACP sintaza - Gliceronfosfat O-aciltransferaza - Lecitin-holesterol aciltransferaza
Glicerol-3-fosfat O-aciltransferaza - 1-acilglicerol-3-fosfat O-aciltransferaza - 2-acilglicerol-3-fosfat O-aciltransferaza - ABHD5B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6