Beta-galaktozid transacetilaza

GAT u kompleksu sa KoA i dva molekula/aktivna mesta IPTG

β-galaktozid transacetilaza je enzim koji vrši transfer acetil grupe sa acetil-KoA na β-galaktozide. Kodiran je genom (lacA) u lac operonu bakterije Escherichia coli.[1] Precisza funkcija ovog enzima u okviru lac operona trenutno nije poznata.[2] Njegova kinetika je razjašnjena 1995.[3]

Vidi još

  • Acetiltransferaza

Reference

  1. ^ Wang XG, Olsen LR, Roderick SL (2002). „Structure of the lac operon galactoside acetyltransferase”. Structure. 10 (4): 581—8. PMID 11937062. doi:10.1016/S0969-2126(02)00741-4. 
  2. ^ Roderick SL. (2005). „The lac operon galactoside acetyltransferase”. C R Biol. 328 (6): 568—75. PMID 15950163. doi:10.1016/j.crvi.2005.03.005. 
  3. ^ A. Lewendon; J. Ellis; W.V. Shaw (1995). „Structural and Mechanistic Studies of Galactoside Acetyltransferase, the Escherichia coli LacA Gene Product”. J. Biol. Chem. 270 (44): 26326—31. PMID 7592843. doi:10.1074/jbc.270.44.26326. 

Literatura

  • Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097. 

Spoljašnje veze

  • galactoside+acetyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
  • EC 2.3.1.18
  • p
  • r
  • u
Transferaze: aciltransferaze (EC 2.3)
2.3.1: osim amino-acilne grupe2.3.2: Aminoaciltransferaze2.3.3: konverzija u alkil pri transferu
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6